The South African Pharmacy Council has eased the laws which prohibit chemists from selling HIV home-testing kits for private use.
The Treatment Action Campaign's (TAC) Marcus Low said the changes might help more South Africans to know their HIV status.
Low said that concerns remain around the risks of suicide and lack of counselling for those who test positive.
Listen to the full conversation from The Midday Report with Stephen Grootes:
A lot of people in the country don't know their status.— Marcus Low, TAC's head of policy
This could be a way, for people who would otherwise be uncomfortable testing, to get an HIV test, know their status and take control of their lives.— Marcus Low, TAC's head of policy
The big question is how this will be done. We haven't seen regulation of it yet.— Marcus Low, TAC's head of policy