Naked scientist: Gene immunotherapy could reverse multiple sclerosis

A strategy to prevent and reverse multiple sclerosis (MS) might finally be in sight; a team of researchers has developed has achieved such a feat in mice.

An experiment conducted on mice allowed scientists o target and suppress destructive immune cells that play a role in the development of MS.

According to the study, the therapy reduced clinical symptoms of the condition in mouse models of the disease.

The Naked Scientist, Chris Smith explains.

What is MS? This is where your own immune system attacks your nervous system. What its going for is a clutch of proteins in a substance called myelin....this relentless immune attack slowly strips away the mylen and it means the ability of nerve cells to communicate faithfully to each other is progressively lost.

Chris Smith, The Naked Scientist

Researchers have taken a harmless virus called AAV, put into that virus a genetic cargo in the form of one of the proteins found in your myelen which is normally the target of this immune attack, a protein called MOG

Chris Smith, The Naked Scientist

They inject this into mice with the rodent equivalent of multiple sclerosis and it goes to the liver, the liver cells then make a lot of this MOG protein, and reeducate the immune system.

Chris Smith, The Naked Scientist

Click on the link below to listen to the full audio.....


This article first appeared on 702 : Naked scientist: Gene immunotherapy could reverse multiple sclerosis


Recommended

by NEWSROOM AI

CapeTalk welcomes all comments that are constructive, contribute to discussions in a meaningful manner and take stories forward.

However, we will NOT condone the following:

  • Racism (including offensive comments based on ethnicity and nationality)
  • Sexism
  • Homophobia
  • Religious intolerance
  • Cyber bullying
  • Hate speech
  • Derogatory language
  • Comments inciting violence.

We ask that your comments remain relevant to the articles they appear on and do not include general banter or conversation as this dilutes the effectiveness of the comments section.

We strive to make the CapeTalk community a safe and welcoming space for all.

CapeTalk reserves the right to: 1) remove any comments that do not follow the above guidelines; and, 2) ban users who repeatedly infringe the rules.

Should you find any comments upsetting or offensive you can also flag them and we will assess it against our guidelines.

CapeTalk is constantly reviewing its comments policy in order to create an environment conducive to constructive conversations.

Read More
Why do you scream when you fall? The Naked Scientist explains

Why do you scream when you fall? The Naked Scientist explains

The Naked Scientist also shares why dart frogs don't poison themselves and the science behind wheels on an airplane.

Naked Scientist: 3D printing rhino horns is a good idea but might not work

Naked Scientist: 3D printing rhino horns is a good idea but might not work

A variety of efforts have been proposed to curb poaching but there have been reservations over whether or not 3D prints will help.

Worms, flies and mice may help us age better

Worms, flies and mice may help us age better

The Naked Scientist, Chris Smith, explains how chemicals released by gut microbes help worms, flies and mice age better.

The Naked Scientist reveals how birds are able to find their way around

The Naked Scientist reveals how birds are able to find their way around

Every week The Naked Scientist offers listeners the opportunity to probe his brain on anything weird and quirky.

Plants have a body clock just like humans says The Naked Scientist

Plants have a body clock just like humans says The Naked Scientist

Every week The Naked Scientist offers listeners the opportunity to pick his brain on anything weird and quirky.

Why does alcohol keep us up at night and does sweat differ in the body?

Why does alcohol keep us up at night and does sweat differ in the body?

The Naked Scientist answers these questions and more with Eusebius McKaiser...

Popular articles
More arrests are imminent in connection with the cash-in-transit heists - Hawks

More arrests are imminent in connection with the cash-in-transit heists - Hawks

Seven suspects were arrested in Limpopo in less than 24 hours after a cash-in-transit vehicle was blown up in the province.

Consumers beware of illegal, deadly weight-loss products

Consumers beware of illegal, deadly weight-loss products

Consumer journalist Wendy Knowler and a medical testing expert put several harmful weight-loss products under the microscope.

Madiba’s private secretary Zelda la Grange opens up about money (hers and his)

Madiba’s private secretary Zelda la Grange opens up about money (hers and his)

Bruce Whitfield interviews La Grange about her and Madiba's attitude to money (hopes and fears, successes and failures, etc.)

Criminals targeting homes with aluminium windows, warns neighborhood watch

Criminals targeting homes with aluminium windows, warns neighborhood watch

The Panorama, Welgelegen and Plattekloof Neighbourhood Watch has identified a new house break-in trend.

‘I started my thriving business with R5000 (and made a profit in the 1st month)’

‘I started my thriving business with R5000 (and made a profit in the 1st month)’

After 3 years there are 3 Nic Harry stores (incl online) that sell 100 000 pairs of socks in over 20 countries around the world.

5 contributing factors to the Western Cape's growing green economy

5 contributing factors to the Western Cape's growing green economy

GreenCape CEO Evan Rice unpacks why our province is seeing a great deal of success with sustainable energy projects.